Can I put the storage drive on a mac, and point the plex server there?



I currently have a 4tb my passport drive on the Nighthawk x10 router. It was previously on a mac mini 2013 running high sierra, using iTunes. I have iTunes pointing to the readyshare on the Nighthawk, but I think this could be causing drops and reconnects that are corrupting the movie files. Is it possible to put the storage back on the mac mini and point the plex server there for media files? I have not been able to make it work so far.