No it does not from my testing. I could not get it to install cleanly, and I was left with Settings are unavailable.
I have verified that PMS-1.28.2.6151 installs and works as intended on macOS 10.14.6 Mojave on an x64 Mac Mini (2018).
I haven’t tried to downgrade a 1.29.x, but I expect that to work with a certain amount of effort.
As another option, a lot of you can restore your PMS and metadata from Time Machine. If you do this, all the folders and files that PMS uses are
~/Library/Application Support/Plex Media Server
~/Library/Caches/PlexMediaServer
~/Library/Logs/Plex Media Server
~/Library/Preferences/com.plexapp.plexmediaserver
/Applications/Plex Media Server
It’s a beta, and I believe I read in another thread that MovieFan.Plex did not encounter these errors during QA testing.
I always suggest people don’t change their software after summer unless you can afford to have it malfunction through new years. Folks generally come back from vacation and set things ablaze in September or October when they get randy 
