Just wanted to note that Sonos integration can actually suffer because of this if the device Plex is running on has multiple NICs. One example given in a topic over in the Plex for Sonos area was someone who has their Plex server connected to a SAN as well as their LAN… and Plex was telling their Sonos devices to connect using the SAN interface instead of the LAN interface… and he has a firewall in place to prevent that from being possible (which would make sense - devices don’t connect to the SAN, servers do; devices connect to the servers).
Also, many NAS devices are multi-homed these days, either with multiple interfaces that can be connected to different networks, or with virtualization built-in that can provide additional virtual interfaces. Having the ability to bind Plex to a particular interface is still something needed, years after this topic was created. Still hoping there’s a chance, somewhere out there…
And yes, I know there’s a workaround setting to tell Plex what interface should be preferred… and IMHO it’s just that, a workaround. Let me control what interface(s) Plex listens on. If I want it to be listening on multiple interfaces, THEN that setting might prove to be handy. But if I only want it listening on one interface in the first place, let me set it up that way.