iOS and tvOS apps were updated in September to “Support IPv6 server addresses”
And indeed, if you add “includeIPv6=1” to an authenticated request to https://plex.tv/api/resources, if a server is properly configured for IPv6, you should see an IPv6 address along side IPv4 addresses:
<Connection protocol="http" address="2607:5300:de:ad:be:ef" port="32400" uri="http://[2607:5300:de:ad:be:ef]:32400" local="0"/>
So it looks to me like work is being done here, and with the right combination of server and client support, IPv6 remote access is working (I can confirm I see this in practice from Apple clients).