Every other Plex release, I am hopeful and turn on Remote Access and typically get Fully accessible outside your network in the Settings dialogue. However, when I try to access my plex server from anywhere else, I get a No Internet Connection error. Remote access never worked for me - for almost 10 years now.
As this closed request mentioned, I do suspect the issue is with DS-Lite.
In the hope that IPv6 eventually gets “fixed” and allows remote access to my Plex server, I wanted to give this thread a bump up.