Ok there seems to be a bug in the remote access-part here. I’ve just read this post here:
He also mentions that the remote access works but it still shows that remote access is not possible. So everything is just perfekt, thanks for your help.
For everbody else running into this problem:
custom access url: https://example.myplexdomain.com:443
secure connection: prefered
network: remote connections enabled, manual port 443
After that remote access shows still “not working” but it works.