Gentlemen.
the new handbrake is bulletproof and these settings are pretty much how you use it for everything - almost.
Trust me.
I’ve even changed slightly from this, but only increasing bit rates a bit - isn’t anything to re-write a guide over - trust me on that one as well. It’ll probably be the first thing you do - and that’s fine - to a point.
I ran into the Nightmare Scenario in Family Guy World recently. That’s because Fox Sucks (they pieced the S01-S05 DVDs together out of spare parts they had laying around), but I haven’t noticed any badness much anywhere else.