How can I move the Plex Media Server folder on my C drive

You can do that with some registry editing…

  1. Stop PMS
  2. Copy the PMS data folder (C:\Users\<user>\AppData\Local\Plex Media Server\) to a new location (e.g. D:\Data\Plex Media Server\)
  3. Open the registry editor and navigate to `HKEY_CURRENT_USER\Software\Plex, Inc.\Plex Media Server
  4. Find the entry LocalAppDataPath – if it doesn’t exist… create it
  5. Set the entry to the new target path (D:\Data\Plex Media Server\ based on the example above)
  6. Save your changes to the Registry
  7. Restart the Plex Media Server
  8. After confirming Plex is using the new location you can delete the original Plex App-Data folder

Important: If you copy the data folder while Plex is still running, you can end up with a corrupted database… so make sure to shut down the Plex Media Server before starting this!!

https://support.plex.tv/articles/201105343-advanced-hidden-server-settings/

Edit: I just figured there’s already a more extensive description (incl. some pics) in the Tips & Tricks section: