As pointed out by @WilhelmStroker, Plex have been giving their argument as for why they won’t support ISO disc images for years in the support article linked above.
There’s been similar requests on that exact matter which have been rejected in the past. The same will go for this one.
@BeattifulCadaver : Plex will also deal with raw rips of discs that have not been optimized or transcoded (leaving the media itself untouched compared to the version encoded on the disc) . The main argument here is the separate disc navigation — personally I’m not missing forced ads during the disc being loaded, unwanted trailers or prerolls (beyond what I’ve configured my server to show)…
