Plex running very slow, having issues with metadata, streams randomly stop

Server Version#: 1.21.1.3830
Player Version#: Fire TV/Web 4.47.3

Since latest kernel update on Centos 8 Stream I am seeing this in com.plexapp.system.log on a frequent basis and plex is painfully slow and often stops responding - any suggestions on how to further diagnose?

I am running with the official plex docker - plexinc/pms-docker:beta

2021-01-03 12:51:02,154 (7f442a7fc700) :  CRITICAL (agentservice:784) - Exception notifying the media server (most recent call last):
  File "/usr/lib/plexmediaserver/Resources/Plug-ins-6c22540d5/System.bundle/Contents/Code/agentservice.py", line 782, in notify_thread
    HTTP.Request(url, cacheTime=0, immediate=True, data=xml)
  File "/usr/lib/plexmediaserver/Resources/Plug-ins-6c22540d5/Framework.bundle/Contents/Resources/Versions/2/Python/Framework/api/networkkit.py", line 194, in Request
    method=method,
  File "/usr/lib/plexmediaserver/Resources/Plug-ins-6c22540d5/Framework.bundle/Contents/Resources/Versions/2/Python/Framework/api/networkkit.py", line 67, in _http_request
    req = self._core.networking.http_request(url, *args, **kwargs)
  File "/usr/lib/plexmediaserver/Resources/Plug-ins-6c22540d5/Framework.bundle/Contents/Resources/Versions/2/Python/Framework/components/networking.py", line 346, in http_request
    return HTTPRequest(self._core, url, data, h, url_cache, encoding, errors, timeout, immediate, sleep, opener, follow_redirects, method)
  File "/usr/lib/plexmediaserver/Resources/Plug-ins-6c22540d5/Framework.bundle/Contents/Resources/Versions/2/Python/Framework/components/networking.py", line 118, in __init__
    self.load()
  File "/usr/lib/plexmediaserver/Resources/Plug-ins-6c22540d5/Framework.bundle/Contents/Resources/Versions/2/Python/Framework/components/networking.py", line 158, in load
    f = self._opener.open(req, timeout=self._timeout)
  File "/usr/lib/plexmediaserver/Resources/Python/lib/python2.7/urllib2.py", line 429, in open
    response = self._open(req, data)
  File "/usr/lib/plexmediaserver/Resources/Python/lib/python2.7/urllib2.py", line 447, in _open
    '_open', req)
  File "/usr/lib/plexmediaserver/Resources/Python/lib/python2.7/urllib2.py", line 407, in _call_chain
    result = func(*args)
  File "/usr/lib/plexmediaserver/Resources/Python/lib/python2.7/urllib2.py", line 1228, in http_open
    return self.do_open(httplib.HTTPConnection, req)
  File "/usr/lib/plexmediaserver/Resources/Python/lib/python2.7/urllib2.py", line 1201, in do_open
    r = h.getresponse(buffering=True)
  File "/usr/lib/plexmediaserver/Resources/Python/lib/python2.7/httplib.py", line 1148, in getresponse
    response.begin()
  File "/usr/lib/plexmediaserver/Resources/Python/lib/python2.7/httplib.py", line 448, in begin
    version, status, reason = self._read_status()
  File "/usr/lib/plexmediaserver/Resources/Python/lib/python2.7/httplib.py", line 404, in _read_status
    line = self.fp.readline(_MAXLINE + 1)
  File "/usr/lib/plexmediaserver/Resources/Python/lib/python2.7/socket.py", line 480, in readline
    data = self._sock.recv(self._rbufsize)
timeout: timed out

Any assistance would be very much appreciated!

Seems the Plex Ninjas have taken a break.

Got to the bottom of it should anyone else see similar unexplained issues, it was not network where I was focusing my efforts.

Turns out that running sqlite on an NFS share is a very bad idea due to locking mech.

Moved the k8s mount for DB files to iSCSI and it all whips along nicely now.