Lots of posts here in this thread - (I will look the set of logs we have in the thread)
We have resolved an issue already in 1.18.6.2368 - see release note which mentions the fix for the lockup that has been seen in logs from users
Anyone still with issues after the update to 1.18.6.2368, please see
https://support.plex.tv/articles/201643703-reporting-issues-with-plex-media-server/
https://support.plex.tv/articles/200250417-plex-media-server-log-files/