@aesposit0 what operating system? linux hardware decoding is not currently supported, so you won’t get gpu help for decoding 4k material.
@JasonNalley this is false, plex does fully support nvidia gpu’s on windows, and it supports nvidia encode on linux (not decode on linux).
you both might find some useful info @ Plex, 4k, transcoding, and you - aka the rules of 4k - a FAQ
all that to say, hardware transcoding is not without issues, so if are using a supported os/gpu, then you post the exact setup and full details along with logs and any helpful screenshots.
also, searching the forum for others with the same problem, may also help you save time with a known issue and/or solution.