Is there a way to install Plex on the DS218Play?

If you want to access from outside your local network, you must also redirect port 16621. Greetings.

Hi, I am struggling with this too. What do you mean by “redirectioned in my router to the port 32400 tcp/udp the ip of my Synology”?
Open the Port 32400 in the router??

port 16621 is not a standard, fixed Plex port. That’s most likely UPnP and therefore transient. No need to add it.

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On your modem/router, if it does not have UPnP/NAT-PMP,

Create a manual Port Forwarding rule to forward port 32400 to the IP address of your Syno also port 32400. Protocol is TCP. UDP is not required.

Ok. Thanks you.