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Shut down the server
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copy the whole Plex data folder from one user’s profile folder to the other.
(or: copy it onto its own dedicated partition or hard drive. Details here: [HowTo] An extended guide on how to move the Plex data folder on Windows ) -
Save the registry branch from one user and import the .reg file while logged into the other.
https://support.plex.tv/articles/201539237-backing-up-plex-media-server-data/