You need to use an external streaming box connected to the Denon AVR.
Streaming Device <-- HDMI --> Denon <-- HDMI-ARC --> Samsung TV
HDMI-ARC does not have the bandwidth to pass lossless audio. That is why you cannot pass dts-HD/dts:X and TrueHD/TrueHD + Atmos using the Plex app on the TV.
The Denon 2100 does not support Dolby Atmos nor dts:X audio. Also, from what I can find online, your TV has 4K resolution, but does not support HDR.
You’ve multiple choices for a client. It depends on whether or not you want support for Atmos audio.
2019 Nvidia Shield Pro (specs)
The Nvidia Shield is the only off the shelf streaming box that will passthrough TrueHD, including TrueHD + Atmos, dts:X, and dts-HD MA.
The 2019 Shield Pro supports HDR10 and Dolby Vision. Earlier models are HDR10 only.
Do not buy the non-Pro (tube) model. There are multiple reports in the forum of problems with high bit-rate movies.
AppleTV 4K (specs)
The AppleTV 4K converts TrueHD 5.1/7.1 to PCM 5.1/7.1 on the AppleTV (no transcoding in Plex). PCM is lossless, so there is no quality loss. Your Denon will show “Multi-Channel In” instead of TrueHD. Atmos information is lost in the process.
EDIT (17 Nov 2020): An update based on this thread. Plex Media Server transcodes TrueHD 7.1 audio to FLAC 7.1 and sends it to the Apple TV 4K. The ATV4K then converts FLAC 7.1 to PCM 7.1 and sends the audio to attached receiver via HDMI. The end result is the same, TrueHD ends up as PCM, and Atmos information is lost in the process.
dts audio is also converted to multi-channel PCM on the AppleTV.
Edit: The AppleTV decodes the dts core audio. The HD extension is discarded. Reference.
Roku Ultra
Roku devices passthrough dts audio. For dts-HD audio, they passthrough the dts 5.1 core, the “-HD” part is discarded.
For TrueHD, information I found online says a Roku sends either Dolby Digital or Dolby Digital Plus to attached devices. It was unclear if the conversion was via transcoding in Plex or happened on the Roku device. The Roku developer site does not list TrueHD as a supported audio format.
Amazon FireStick 4K & other FireTV Devices (specs)
No dts passthrough. dts is converted on the device to either Dolby Digital or Dolby Digital Plus, depending on device settings.
No TrueHD passthrough. TrueHD will be transcoded to AAC by the Plex Media Center. It will then be sent to your Denon as DD or DD+, depending on device settings.
Given the requirements listed above, the Amazon FireTV devices are not a good fit for you.
Windows Personal Computer with Plex for Windows or Plex Media Player
Both Plex for Windows and Plex Media Player support passthrough for dts-HD and TrueHD audio.
Plex Media Player, PMP, has a Home Theater PC type interface that looks similar to that on AndroidTV devices. Note that PMP is not receiving new features, so some Plex features such as Watch Together, Intro Skip, etc are not available. PMP is basically in maintenance mode.
Plex for Windows looks similar to Plex Web. It does receive updates for new features.
AFAIK, the Mac versions of both have feature parity with their Windows counterparts. However, the Mac versions do not support TrueHD passthrough (Apple restriction).