Hi, I have recently been experiencing the same issue. Running Plex docker in portainer on OpenMediaVault 5.4.3.1. all worked until Plex version 1.19.2.2737. Upgraded my Docker to Plex 1.19.3.2764 but still have the Error. A short console dump below, and full logs attached. any pointer would be welcome 
May 19, 2020 13:16:38.479 [0x7faff77fe700] Error — ClientProfileExtra: video transcode target already exists for streaming hls
May 19, 2020 13:16:38.492 [0x7faff77fe700] Error — [FFMPEG] - Cannot load libcuda.so.1
May 19, 2020 13:16:38.492 [0x7faff77fe700] Error — [FFMPEG] - Could not dynamically load CUDA
May 19, 2020 13:16:38.495 [0x7faff77fe700] Error — [FFMPEG] - Cannot load libcuda.so.1
May 19, 2020 13:16:38.495 [0x7faff77fe700] Error — [FFMPEG] - Could not dynamically load CUDA
May 19, 2020 13:16:38.551 [0x7fb0797fa700] Error — ClientProfileExtra: video transcode target already exists for streaming hls
May 19, 2020 13:16:38.565 [0x7fb0797fa700] Error — [FFMPEG] - Cannot load libcuda.so.1
May 19, 2020 13:16:38.565 [0x7fb0797fa700] Error — [FFMPEG] - Could not dynamically load CUDA
May 19, 2020 13:16:38.567 [0x7fb0797fa700] Error — [FFMPEG] - Cannot load libcuda.so.1
May 19, 2020 13:16:38.567 [0x7fb0797fa700] Error — [FFMPEG] - Could not dynamically load CUDA
May 19, 2020 13:16:38.783 [0x7faff77fe700] Error — Error creating directory “AppData/Plex”: Permission denied
May 19, 2020 13:16:38.785 [0x7faff77fe700] Error — Error creating directory “AppData/Plex”: Permission denied
May 19, 2020 13:16:38.805 [0x7fafecff9700] Error — [Transcoder] Unrecognized option ‘crf:0’.
May 19, 2020 13:16:38.805 [0x7fb0797fa700] Error — [Transcoder] Error splitting the argument list: Option not found
May 19, 2020 13:16:38.813 [0x7fb01affd700] Error — Error creating directory “AppData/Plex”: Permission denied
May 19, 2020 13:16:39.323 [0x7fafeaff5700] Warning — Got a request to stop a transcode session without a session GUID (or with an invalid one).Plex Media Server Logs_2020-05-19_13-23-10.zip (3.6 MB)