Having trouble enabling remote access.

I’m running Plex on a 2-bay QNAP NAS (TS-231+), I’ve tried disabling the routers and the McAfee firewalls, not sure what to look at at next? I’ve tried running the server software on a computer on the same home network, and get the same issue. Status is green when the server software is installed, but remote connections get messages about relayed or unsecured connections. After any restart, settings change, the outside connectivity status goes red and stays that way. Looking for a point in some direction, or any kind of troubleshooting guide if its out there.