I mentioned I have seen error 52 when processes get killed - well this is exactly that
So have you tampered with the system settings to change the value this variable has ?
PLEX_MEDIA_SERVER_MAX_PLUGIN_PROCS
and where did you get the recommendation to set it to 1 from ?
Extracts from the log
We have a plexmusic request here
Mar 11, 2016 22:08:28 [0x7fd14bfff700] DEBUG - HTTP requesting GET http://127.0.0.1:53598/:/plugins/com.plexapp.agents.plexmusic/messaging/function/X0FnZW50S2l0OlVwZGF0ZU1ldGFkYXRh/Y2VyZWFsMQoxCmxpc3QKMApyMAo_/Y2VyZWFsMQoxCmRpY3QKMTAKczIKZW5zNApsYW5nYjFzNQpmb3JjZWIwczgKcGVyaW9kaWNzNQozMjEyNnM0CmRiaWRpMApzNwp2ZXJzaW9ubnMxMApwYXJlbnRHVUlEbnM4CnBhcmVudElEczYKQXJ0aXN0czEwCm1lZGlhX3R5cGVzNzIKY29tLnBsZXhhcHAuYWdlbnRzLnBsZXhtdXNpYzovL2dyYWNlbm90ZS9hcnRpc3QvMDUzNkQ5OUYwQTI0NkExOT9sYW5nPWVuczQKZ3VpZHMzMwpncmFjZW5vdGUvYXJ0aXN0LzA1MzZEOTlGMEEyNDZBMTlzMgppZHIwCg__
It gets queued
Then we have a request to the lastfm agent
Mar 11, 2016 22:08:28 [0x7fd1487ff700] DEBUG - Request: [127.0.0.1:33799] GET /:/plugins/com.plexapp.agents.lastfm/messaging/function/TWVzc2FnZUtpdDpBcnRpc3RTZWFyY2g_/Y2VyZWFsMQoxCmxpc3QKMApyMAo_/Y2VyZWFsMQoyCmRpY3QKbGlzdAozCnMyCmVuczQKbGFuZ3IxCnM2CmFsYnVtc3M4CldhcmRydW5hczYKYXJ0aXN0MQpzOQpZZ2dkcmFzaWxyMAo_ (13 live) GZIP
We notice it is not running so we find oldest agent process to kill but there is only one - plexmusic
Mar 11, 2016 22:08:28 [0x7fd1487ff700] DEBUG - Starting file watcher for com.plexapp.agents.lastfm
Mar 11, 2016 22:08:28 [0x7fd1487ff700] DEBUG - Plug-in limit of 1 exceeded.
Mar 11, 2016 22:08:28 [0x7fd1487ff700] DEBUG - * Bringing down the older plug-in: com.plexapp.agents.plexmusic.
Mar 11, 2016 22:08:28 [0x7fd1487ff700] DEBUG - Stopping [com.plexapp.agents.plexmusic].
Mar 11, 2016 22:08:28 [0x7fd1487ff700] DEBUG - [com.plexapp.agents.plexmusic] Killing.
and the killing of the process results in Error 52 for the plexmusic request
Mar 11, 2016 22:08:28 [0x7fd14bfff700] ERROR - Error issuing curl_easy_perform(handle): 52
Please change the value for the environment variable back to 6
It was i understand introduced for very slow NAS systems to allow some tweaking but that needs advice from Plex Devs and should not be a user decision