Oh boy, no it is not, thankfully! I tracked it down to a GPU power-save script I had setup which wasn’t detecting Plex as actually using the GPU anymore so it was forcing the GPU into low-power state thus crashing playback. – I also had DVR recording issues too.
I was able to fully solved tho - see here: DVR recordings all stopping after exactly 12 minutes - #32 by CorneliousJD