I’ll quickly describe the current infrastructure of Plex and other semi-associated apps:
Plex runs on baremetal install of Ubuntu 19.10 (HP EliteDesk 800 i5-8500T w/ QuickSync) with a single NIC on the motherboard with IP 172.22.1.192.
I run other associated apps inside of VMWare CentOS VM on a Windows 10 host (this has been a temporary setup until migration to Unraid). The most relevant apps include an nginx reverse proxy, ombi, radarr, sonarr. The Windows 10 host has IPs 172.22.1.197 and 172.22.1.198. The VM has IP 172.22.1.191.
Throughout all of the crashes, the reverse proxy has not been setup in the Network settings of Plex, so traffic was coming in directly to the Plex port exposed through the router. I was testing it on and off this weekend, but this problem has persisted before any Plex traffic was proxied through nginx, so I don’t think that app is particularly relevant to this issue at the moment. Some of the other API calls coming from 172.22.1.191 are probably from Ombi, sonarr, and radarr, so the amount of traffic should be light.
It looks like LRO is disabled on the baremetal Plex host though:
mike@Mr-Meeseeks:~$ ethtool -k eno1 | grep large-receive-offload
large-receive-offload: off [fixed]