Unable to connect to server

I am not new to Plex and generally have 3 Servers up and running. I just started having this issue today and have never encountered it in over 3 years of running Plex. Changed nothing about this server and not even aware of a Plex Server update running on this machine in the last few weeks. Any suggestions would be greatly appreciated.

I am having this issue as well on the latest Plex Pass release. Happened out of nowhere.

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