You cropped off the Plex client information.
You are probably running into the limitations of various Plex clients and the limitations of running Plex on systems with low power CPUs.
Example:
Plex Web does not support direct playing VOBSUB subtitles due to the limitations of web browsers.
With Plex Web, when playing a video with VOBSUB subtitles, Plex Media Server must transcode the video and burn the subtitles into the video stream (burn = adding the subtitles to the video frame).
The burning process uses the CPU, even when the video is transcoded using the GPU. Furthermore, the process is single threaded, so it cannot take advantage of multiple CPU cores.
The Celeron J3455 in the DS918+ is not strong enough to burn subtitles in real time for all video resolutions. It can do so for 480p & 720p, but will fail for some 1080p video.
As a result, playback will frequently pause (buffer) while the client waits for the CPU to catch up and process additional video frames.
With respect to Plex Web, if you are using a Windows, Mac, or Linux system, consider using Plex Desktop instead. It will direct play most audio/video/subtitle formats, negating the need Plex Media Server to transcode the video and burn subtitles.
Unfortunately, Plex Dashboard does not show when subtitle burning is occurring.
Consider using Tautulli. It has a dashboard similar to Plex’s, but it displays additional information, including when subtitle burning is occurring.
Tautulli Dashboard: Showing subtitle burning when using VOBSUB subtitles in Plex Web

Tautulli Dashboard: Same video, same client, no subtitles.

Tautulli Dashboard: Same video, using Plex Desktop instead of Plex Web
