Last week Plex server suddenly disappeared from my Roku and all of my other devices.
I have rebooted my router, I can still it on the computer that the server is installed on; I have updated the software to the latest version, and logged in and deleted the registry; the only thing I haven’t done yet is reinstalling it.
Verify that Windows hasn’t changed the network connection to ‘public’.
It must be set to ‘private’, or all the necessary ports are closed for Plex.