I can confirm that on 918+ I had this issue since 2 PMS updates ago. More precisely, since version 1.18.4. In other words, the PMS on my 918+ goes AWOL with the following 2 packages, even though the DMS reports the PMS service as running:
PlexMediaServer-1.18.4.2171-ac2afe5f8-x86_64.spk
PlexMediaServer-1.18.5.2309-f5213a238-x86_64.spk
As a result, I have uninstalled PMS using the Package Center (I have not touched anything else such as shares, files or user accounts) and installed version 1.18.3; more precisely: PlexMediaServer-1.18.3.2156-349e9837e-x86_64.spk.
I can confirm that over the last couple of days I’ve had no issues on 918+ compared to before when I had to restart the PMS service at least once a day.
A note that you cannot install 1.18.3 over a later version. You have to uninstall that PMS version first. Nothing was affected by this process; all libraries, art work, etc. remained untouched.
Bottom line: it seems like version 1.18.4 and 1.18.5 affect somehow Synology devices, however, not all of them. My 3615xs is fine with version 1.18.5 and the same DSM version 6.2.2 so I’m not sure what causes this weird behaviour on my 918+.
Hope that helps.