Plex server is unreachable - only on a single client

Server Version#: 1.20.1.3252
Player Version#: Plex Web 4.34.4

I have server on a Win10 machine. I usually log into the app.plex.tv from my other desktop (Win10 Pro). A couple of months ago, I started getting Plex Server is unreachable on this box. No other access issues on any device (mostly Android/Chromecast or my Samsung BluRay). But it is absolutely unreachable on this box. Doesn’t work on Chrome, MS Edge (new) or old Internet Explorer. I have already done DB repair and set up port forwarding, no change.

Today for the first time I tried Firefox. It fired right up, asked for my login info and boom, working. So why the heck can’t I get in via MS Edge browser (my default - don’t judge). It really seems that there is some kind of block only on this box (from a Windows update I’d guess). Any ideas where to look. Keep in mind I’ve tried everything from the forums (not much to go on there, Plex seems to not be listening so it’s a matter of the blind leading the blind here)…

If I could just reach the server again from another browser I’d be happy. Granted I’m stoked I can get in via Firefox after being locked out last 2 months, but still…

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