Update…after searching around more…I found that someone else was having similar issues
…I went into my IOS app and adjusted the Quality settings (Limit on Cellular Data was set to 0.7 Mbps, 320p - setting it to the max 720p was still failing, so I had to turn it off)…and Automatically Adjust Quality kept causing it to fail as well…when I set Remote Streaming to 10Mbps, 1080p HD I was able to get a 4K DTS-X file to transcode and play. Clearly Plex has made some updates to the Transcoding “software”…as this has worked without any adjustments for years. Anyone know of anything…???