Two Tuner boxes supported?

For various reasons I have two antennae with 2 downleads (combining them was a fail). So I want to connect a HD Homerun to each of the downleads, does Plex support separate tuner boxes on 1 server instance? Would like to check before I get the 2nd one.
Thanks

I have two tuner boxes.

Yes, you can use several HDHR devices at once in Plex.

Yes, but you are limited to a single EPG source for both.