Running Plexamp 4.2.1 on desktop (macOS 12.3.1 on a MBPro 2019), I’ve found that the seeking on the seekbar will sometimes be misaligned with the mouse cursor after resizing the width of the PlexAmp window.
Sometimes it’s just a couple of pixels out. Sometimes the difference can be hundreds.
This happens on both a “standard” and “retina” display, so I don’t believe DPI scaling or similar is related. (In fact, the issue will persist if I move PlexAmp between screens – yay for consistency!..?)
This mostly seems to happen when Plexamp is over a certain width. When the window is skinny, it seems less likely to happen (although I’ve seen it once or twice once I started trying to reproduce it
). I’ve included a screenshot of the issue on one such width to give an idea of how wide I mean:

Quitting and relaunching seems to fix it at a given width, so the bug appears to be related to the act of resizing.