Plex clients can't find local Plex Server on a machine with a corporate VPN (GlobalProtect)

My company mandated a specific VPN client to be used in my machine (GlobalProtect). I use this laptop at home, with a QNap NAS running a Plex server. Since this VPN change took place, none of the Plex clients on that machine can find my NAS Server - that includes the Web-based Plex client as well as the Win10 Plex app. However, I can still access QNap’s web-based management site on my NAS from this corporate machine, so this issue is only affecting Plex.

Other personal Win10 machines at home without such VPN can find my Plex server without an issue. Same from my Win10 mobile device.

Is there any settings I need to change somewhere in my corporate machine so its Plex clients can find my Plex Server?

I’m running latest versions of clients and server on all those machines.

Thanks!

Knowing you home’s external IP try doing a traceroute from this laptop to your home router. What happens?
If you can tracert properly then try direct access to your Plex server with http://ipaddress:32400 in a web browser.

Does that work?

What you need is the VPN configuration to allow your local LAN. This means the netmask and configuration cannot make the tunneling (tun) adapter the default. The tunnel must only apply for destinations defined on the corporate network. Straight forward entries in the routing table will handle this for you.

To be clear, you most likely will not have Remote Access (external sharing) because PMS + Plex.tv + VPN is very problematic when a tunnel device (the exit point on the other end of the tunnel is usually very restricted and firewalled)