I have the same issue. The version I used before this one worked, and then didn’t. I then uninstalled that version, installed “Plex-1.39.1.2763-300bb607-x86_64”. Plex app tries to start, dies. Nothing in the log appears to be wrong. Rebooted. No dice.
Jan 22, 2022 11:48:19.983 [10432] INFO - Starting Plex version: 1.39.1.2763-300bb607
Jan 22, 2022 11:48:19.983 [10432] INFO - Running on: Windows 10 Version 2009 [10.0.19042] x86_64
Jan 22, 2022 11:48:19.983 [10432] INFO - Happy Plexing!
Jan 22, 2022 11:48:19.982 [11172] INFO - [OpenGL] Selected angle renderer.
Jan 22, 2022 11:48:19.982 [11172] INFO - [OpenGL] Default surface format version: 2.0
Jan 22, 2022 11:48:19.982 [11172] INFO - [OpenGL] Selecting surface format version: 3.0; profile: 1
Jan 22, 2022 11:48:20.018 [11172] INFO - [OpenGL] Testing surface format version: 3.0
Jan 22, 2022 11:48:20.019 [11172] INFO - [OpenGL] Setting default surface format
Jan 22, 2022 11:48:20.019 [11172] WARN - [OpenGL] Warning: Setting a new default format with a different version or profile after the global shared context is created may cause issues with context sharing.
Jan 22, 2022 11:48:20.019 [11172] INFO - [Settings] Web inspector port 0
Jan 22, 2022 11:48:20.034 [11172] INFO - [NanoServer] Starting nano server.
Jan 22, 2022 11:48:20.034 [11172] DEBUG - [NanoServer] Setting app support dir to C:/Users/bubba/AppData/Local/Plex
Jan 22, 2022 11:48:20.036 [11172] INFO - [NanoServer] Found available port: 32700
Jan 22, 2022 11:48:20.036 [11172] INFO - [NanoServer] Changing nano server port from 0 to 32700.
Jan 22, 2022 11:48:20.036 [11172] DEBUG - [NanoServer] Setting listener port to 32700
Jan 22, 2022 11:48:20.036 [11172] DEBUG - [NanoServer] Setting environment up.