I have the same issue too. I had to boot my Mac into safe mode to disable PMS launching on startup. However, as soon as I open Plex Media Server again manually, my system completely crashes seconds after and restarts. You can download my Plex logs here.
And here’s the crash report I get after my Mac restarts:
panic(cpu 0 caller 0xffffff801debfb71): assertion failed: (MBUFQ_EMPTY(&cfq->q_mq) && cfq->q_start == cfq->q_end) || (!MBUFQ_EMPTY(&cfq->q_mq) && cfq->q_start != cfq->q_end), file: /AppleInternal/BuildRoot/Library/Caches/com.apple.xbs/Sources/xnu/xnu-7195.50.7/bsd/net/content_filter.c, line: 1089
Backtrace (CPU 0), Frame : Return Address
0xffffff803175b6f0 : 0xffffff801d6bc66d
0xffffff803175b740 : 0xffffff801d7ff073
0xffffff803175b780 : 0xffffff801d7ef6aa
0xffffff803175b7d0 : 0xffffff801d661a2f
0xffffff803175b7f0 : 0xffffff801d6bbf0d
0xffffff803175b910 : 0xffffff801d6bc1f8
0xffffff803175b980 : 0xffffff801debee1a
0xffffff803175b9f0 : 0xffffff801debfb71
0xffffff803175ba00 : 0xffffff801daadcfe
0xffffff803175ba40 : 0xffffff801daae008
0xffffff803175bbd0 : 0xffffff801daac4ef
0xffffff803175bc20 : 0xffffff801daa921c
0xffffff803175bc90 : 0xffffff801dc2ecf9
0xffffff803175bce0 : 0xffffff801dca8c20
0xffffff803175be00 : 0xffffff801dc7d4c8
0xffffff803175be30 : 0xffffff801dc77e35
0xffffff803175bee0 : 0xffffff801dc77c47
0xffffff803175bf40 : 0xffffff801dd69ceb
0xffffff803175bfa0 : 0xffffff801d6621f6
Process name corresponding to current thread: ch.tripmode.TripMode.FilterExten
Mac OS version:
20B29
Kernel version:
Darwin Kernel Version 20.1.0: Sat Oct 31 00:07:11 PDT 2020; root:xnu-7195.50.7~2/RELEASE_X86_64
Kernel UUID: 84C6DC45-6B02-335F-9439-5D2A9BC385A4
KernelCache slide: 0x000000001d400000
KernelCache base: 0xffffff801d600000
Kernel slide: 0x000000001d410000
Kernel text base: 0xffffff801d610000
__HIB text base: 0xffffff801d500000
System model name: MacBookPro11,1 (Mac-189A3D4F975D5FFC)
System shutdown begun: NO
Panic diags file available: YES (0x0)
Hibernation exit count: 0
System uptime in nanoseconds: 7200141557131
Last Sleep: absolute base_tsc base_nano
Uptime : 0x0000068c69e141b8
Sleep : 0x0000000000000000 0x0000000000000000 0x0000000000000000
Wake : 0x0000000000000000 0x00000009ef4b172b 0x0000000000000000
last started kext at 188347851126: @ filesystems.smbfs 3.4.1 (addr 0xffffff7fbdab5000, size 434176)
loaded kexts:
com.globaldelight.driver.Boom2Device 1.1
@ filesystems.smbfs 3.4.1
>!AUpstreamUserClient 3.6.8
@ filesystems.autofs 3.0
@ fileutil 20.036.15
>!APlatformEnabler 2.7.0d0
>AGPM 119
>X86PlatformShim 1.0.0
>AudioAUUC 1.70
>!AGraphicsDevicePolicy 6.1.27
@ AGDCPluginDisplayMetrics 6.1.27
>!AHDAHardwareConfigDriver 283.15
>!AHDA 283.15
>pmtelemetry 1
>LuaHardwareAccess 1.0.16
|IOUserEthernet 1.0.1
>usb.!UUserHCI 1
>!A!IHD5000Graphics 16.0.0
|IO!BSerialManager 8.0.1f5
@ Dont_Steal_Mac_OS_X 7.0.0
>!AHV 1
>!ADiskImages2 1
>eficheck 1
>AGDCBacklightControl 6.1.27
>!A!ISlowAdaptiveClocking 4.0.0
>!ACameraInterface 7.6.0
>!ALPC 3.1
>!AThunderboltIP 4.0.3
>!A!IFramebufferAzul 16.0.0
>!ABacklight 180.3
>!ASMCLMU 212
>ACPI_SMC_PlatformPlugin 1.0.0
>!AFIVRDriver 4.1.0
>!AMCCSControl 1.14
|IO!BUSBDFU 8.0.1f5
>!UTCKeyEventDriver 256
>!UTCButtons 256
>!UTCKeyboard 256
>!AFileSystemDriver 3.0.1
@ filesystems.tmpfs 1
@ filesystems.hfs.kext 556.41.1
@ BootCache 40
@ !AFSCompression.!AFSCompressionTypeZlib 1.0.0
@ !AFSCompression.!AFSCompressionTypeDataless 1.0.0d1
@ filesystems.apfs 1677.50.1
>!AAHCIPort 346
>AirPort.BrcmNIC 1400.1.1
@ private.KextAudit 1.0
>!ASmartBatteryManager 161.0.0
>!ARTC 2.0
>!AACPIButtons 6.1
>!AHPET 1.8
>!ASMBIOS 2.1
>!AACPIEC 6.1
>!AAPIC 1.7
@ !ASystemPolicy 2.0.0
@ nke.applicationfirewall 310
|IOKitRegistryCompatibility 1
|EndpointSecurity 1
@ kext.triggers 1.0
>!AGraphicsControl 6.1.27
>DspFuncLib 283.15
@ kext.OSvKernDSPLib 529
|IOSerial!F 11
|IOAVB!F 900.12
@ !AGPUWrangler 6.1.27
|IOSlowAdaptiveClocking!F 1.0.0
>!ASMBusPCI 1.0.14d1
>!AThunderboltEDMSink 5.0.3
>!AThunderboltDPOutAdapter 8.1.4
|IOAccelerator!F2 439.35.4
@ !AGraphicsDeviceControl 6.1.27
>!ABacklightExpert 1.1.0
|IONDRVSupport 585
@ plugin.IOgPTPPlugin 900.11
|IOEthernetAVB!C 1.1.0
>IOPlatformPluginLegacy 1.0.0
>X86PlatformPlugin 1.0.0
>IOPlatformPlugin!F 6.0.0d8
>!AHDA!C 283.15
|IOHDA!F 283.15
|IOAudio!F 300.6.1
@ vecLib.kext 1.2.0
|IOGraphics!F 585
>!ASMBus!C 1.0.18d1
|Broadcom!BHost!CUSBTransport 8.0.1f5
|IO!BHost!CUSBTransport 8.0.1f5
|IO!BHost!CTransport 8.0.1f5
>usb.!UHub 1.2
>!UMultitouch 264
>usb.IOUSBHostHIDDevice 1.2
>usb.cdc 5.0.0
>usb.networking 5.0.0
>usb.!UHostCompositeDevice 1.2
>!AThunderboltDPInAdapter 8.1.4
>!AThunderboltDPAdapter!F 8.1.4
>!AThunderboltPCIDownAdapter 4.1.1
>!ABSDKextStarter 3
|IOSurface 289.3
@ filesystems.hfs.encodings.kext 1
>!AXsanScheme 3
|IOAHCIBlock!S 332
|IOAHCI!F 294
>!AThunderboltNHI 7.2.8
|IOThunderbolt!F 9.3.2
|IO80211!F 1200.12.2b1
|IOSkywalk!F 1
>mDNSOffloadUserClient 1.0.1b8
>corecapture 1.0.4
>usb.!UHostPacketFilter 1.0
|IOUSB!F 900.4.2
>!A!ILpssGspi 3.0.60
>usb.!UXHCIPCI 1.2
>usb.!UXHCI 1.2
>!AEFINVRAM 2.1
>!AEFIRuntime 2.1
|IOSMBus!F 1.1
|IOHID!F 2.0.0
$!AImage4 3.0.0
|IOTimeSync!F 900.11
|IONetworking!F 3.4
>DiskImages 493.0.0
|IO!B!F 8.0.1f5
|IOReport!F 47
|IO!BPacketLogger 8.0.1f5
$quarantine 4
$sandbox 300.0
@ kext.!AMatch 1.0.0d1
|CoreAnalytics!F 1
>!ASSE 1.0
>!AKeyStore 2
>!UTDM 511.40.9
|IOUSBMass!SDriver 184.40.6
|IOSCSIBlockCommandsDevice 436.40.6
|IO!S!F 2.1
|IOSCSIArchitectureModel!F 436.40.6
>!AMobileFileIntegrity 1.0.5
@ kext.CoreTrust 1
>!AFDEKeyStore 28.30
>!AEffaceable!S 1.0
>!ACredentialManager 1.0
>KernelRelayHost 1
|IOUSBHost!F 1.2
>!UHostMergeProperties 1.2
>usb.!UCommon 1.0
>!ABusPower!C 1.0
>!ASEPManager 1.0.1
>IOSlaveProcessor 1
>!AACPIPlatform 6.1
>!ASMC 3.1.9
|IOPCI!F 2.9
|IOACPI!F 1.4
>watchdog 1
@ kec.pthread 1
@ kec.corecrypto 1.0
@ kec.Libm 1
Mod-Edit: moved this into a dedicated thread; the thread you posted in was particularly about Plexamp.