This just started happening today. I open plexamp and I kept getting busy mouse icon every half second and plexamp would not play anything. In task manager I see 4 insatnces of plexamp.exe where one would close and re-open again and again. Rebooted initially, no change. Uninstalled - reinstalled, no change. I can search for music but playing does nothing. I'm running Windows 10 with current updates.
I looked at the log and it appears that plexamp discovers my library on my lan but it the player isn't found in available resources.