Thanks for providing the logs with your OP.
From what I can see, you’re having a complete loss of network (LAN → WAN) connectivity.
There is no route to any host (the adapter is down).
When it comes back up, it cannot resolve host names.
If this is WiFi, there is an issue with signal strength and it dropping out.
If thie is wired, there is a physical connection issue.
Mar 12, 2021 07:48:47.359 [0x7fe5d5cd7700] DEBUG - Request: [192.168.1.161:51241 (Subnet)] GET /player/proxy/poll?deviceClass=pc&protocolVersion=3&protocolCapabilities=timeline%2Cplayback%2Cnavigation%2Cmirror%2Cplayqueues&timeout=1 (3 live) GZIP Signed-in Token (anunez86)
Mar 12, 2021 07:48:47.359 [0x7fe5d5cd7700] DEBUG - Content-Length is -1 (of total: -1).
Mar 12, 2021 07:48:56.328 [0x7fe60f0ed700] DEBUG - EventSource: Failure in IdleTimeout (0 - Success).
Mar 12, 2021 07:48:56.328 [0x7fe60f0ed700] DEBUG - MyPlex: We appear to have lost Internet connectivity, resetting device URL cache.
Mar 12, 2021 07:48:56.328 [0x7fe60f0ed700] ERROR - EventSource: Retrying in 15 seconds.
Mar 12, 2021 07:48:56.921 [0x7fe60edff700] DEBUG - EventSource: Failure in IdleTimeout (0 - Success).
Mar 12, 2021 07:48:56.921 [0x7fe60edff700] ERROR - EventSource: Retrying in 15 seconds.
Mar 12, 2021 07:49:07.359 [0x7fe60f0ed700] DEBUG - Completed: [192.168.1.161:51241] 200 GET /player/proxy/poll?deviceClass=pc&protocolVersion=3&protocolCapabilities=timeline%2Cplayback%2Cnavigation%2Cmirror%2Cplayqueues&timeout=1 (3 live) GZIP 20000ms 5 bytes (pipelined: 9)
Mar 12, 2021 07:49:07.364 [0x7fe60edff700] DEBUG - Auth: authenticated user 1 as anunez86
Mar 12, 2021 07:49:07.364 [0x7fe5d5cd7700] DEBUG - Request: [192.168.1.161:51241 (Subnet)] GET /player/proxy/poll?deviceClass=pc&protocolVersion=3&protocolCapabilities=timeline%2Cplayback%2Cnavigation%2Cmirror%2Cplayqueues&timeout=1 (3 live) GZIP Signed-in Token (anunez86)
Mar 12, 2021 07:49:07.364 [0x7fe5d5cd7700] DEBUG - Content-Length is -1 (of total: -1).
Mar 12, 2021 07:49:11.328 [0x7fe60f0ed700] DEBUG - EventSource: Resolving 97.107.133.152 port 443
Mar 12, 2021 07:49:11.328 [0x7fe60f0ed700] DEBUG - EventSource: Resolved 97.107.133.152 to 97.107.133.152
Mar 12, 2021 07:49:11.922 [0x7fe60edff700] DEBUG - EventSource: Resolving 71-174-233-145.2cf83ecd657e4b7b907af04cdd790b83.plex.direct port 38400
Mar 12, 2021 07:49:26.931 [0x7fe60edff700] DEBUG - EventSource: Resolved 71-174-233-145.2cf83ecd657e4b7b907af04cdd790b83.plex.direct to 71.174.233.145
Mar 12, 2021 07:49:27.364 [0x7fe60edff700] DEBUG - Completed: [192.168.1.161:51241] 200 GET /player/proxy/poll?deviceClass=pc&protocolVersion=3&protocolCapabilities=timeline%2Cplayback%2Cnavigation%2Cmirror%2Cplayqueues&timeout=1 (3 live) GZIP 20000ms 5 bytes (pipelined: 10)
Mar 12, 2021 07:49:27.373 [0x7fe60f0ed700] DEBUG - Auth: authenticated user 1 as anunez86
Mar 12, 2021 07:49:27.373 [0x7fe5d5cd7700] DEBUG - Request: [192.168.1.161:51241 (Subnet)] GET /player/proxy/poll?deviceClass=pc&protocolVersion=3&protocolCapabilities=timeline%2Cplayback%2Cnavigation%2Cmirror%2Cplayqueues&timeout=1 (3 live) GZIP Signed-in Token (anunez86)
Mar 12, 2021 07:49:27.373 [0x7fe5d5cd7700] DEBUG - Content-Length is -1 (of total: -1).
Mar 12, 2021 07:49:29.778 [0x7fe60f0ed700] DEBUG - EventSource: Failure in Connect (113 - No route to host).
Mar 12, 2021 07:49:29.778 [0x7fe60f0ed700] ERROR - EventSource: Retrying in 30 seconds.
Mar 12, 2021 07:49:29.778 [0x7fe60f0ed700] DEBUG - EventSource: Failure in Connect (113 - No route to host).
Mar 12, 2021 07:49:29.779 [0x7fe60f0ed700] ERROR - EventSource: Retrying in 30 seconds.
Mar 12, 2021 07:49:33.186 [0x7fe60e1f8700] DEBUG - NetworkServiceBrowser: SSDP departed after not being seen for 29.751780 seconds: 192.168.1.1 (Fios Router)
Mar 12, 2021 07:49:47.373 [0x7fe60f0ed700] DEBUG - Completed: [192.168.1.161:51241] 200 GET /player/proxy/poll?deviceClass=pc&protocolVersion=3&protocolCapabilities=timeline%2Cplayback%2Cnavigation%2Cmirror%2Cplayqueues&timeout=1 (3 live) GZIP 20000ms 5 bytes (pipelined: 11)
Mar 12, 2021 07:49:47.380 [0x7fe60edff700] DEBUG - Auth: authenticated user 1 as anunez86
Mar 12, 2021 07:49:47.380 [0x7fe5d5cd7700] DEBUG - Request: [192.168.1.161:51241 (Subnet)] GET /player/proxy/poll?deviceClass=pc&protocolVersion=3&protocolCapabilities=timeline%2Cplayback%2Cnavigation%2Cmirror%2Cplayqueues&timeout=1 (3 live) GZIP Signed-in Token (anunez86)
Mar 12, 2021 07:49:47.380 [0x7fe5d5cd7700] DEBUG - Content-Length is -1 (of total: -1).
Mar 12, 2021 07:49:59.779 [0x7fe60edff700] DEBUG - EventSource: Resolving 97.107.133.152 port 443
Mar 12, 2021 07:49:59.779 [0x7fe60f0ed700] DEBUG - EventSource: Resolving 71-174-233-145.2cf83ecd657e4b7b907af04cdd790b83.plex.direct port 38400
Mar 12, 2021 07:49:59.779 [0x7fe60edff700] DEBUG - EventSource: Resolved 97.107.133.152 to 97.107.133.152
Mar 12, 2021 07:49:59.779 [0x7fe60f0ed700] DEBUG - EventSource: Failure in Connect (101 - Network is unreachable).
Mar 12, 2021 07:49:59.780 [0x7fe60edff700] DEBUG - EventSource: Resolved 71-174-233-145.2cf83ecd657e4b7b907af04cdd790b83.plex.direct to 71.174.233.145
Mar 12, 2021 07:49:59.780 [0x7fe60edff700] DEBUG - EventSource: Failure in Connect (101 - Network is unreachable).
Mar 12, 2021 07:49:59.780 [0x7fe60edff700] ERROR - EventSource: Retrying in 60 seconds.
Mar 12, 2021 07:50:01.242 [0x7fe5d7d11700] DEBUG - NetworkServiceBrowser: Parsing SSDP schema for http://192.168.1.1:57122/rootDesc.xml
Mar 12, 2021 07:50:01.242 [0x7fe5d7d11700] DEBUG - HTTP requesting GET http://192.168.1.1:57122/rootDesc.xml
Mar 12, 2021 07:50:01.243 [0x7fe5d7d11700] DEBUG - HTTP 200 response from GET http://192.168.1.1:57122/rootDesc.xml
Mar 12, 2021 07:50:01.244 [0x7fe5d7d11700] DEBUG - NetworkServiceBrowser: found 1 SSDP devices via http://192.168.1.1:57122/rootDesc.xml
Mar 12, 2021 07:50:01.244 [0x7fe5d7d11700] DEBUG - NetworkServiceBrowser: SSDP arrived: 192.168.1.1 (Fios Router)
Mar 12, 2021 07:50:04.779 [0x7fe60f0ed700] DEBUG - HTTP requesting GET https://plex.tv/services/pubsub/servers
Mar 12, 2021 07:50:04.780 [0x7fe60edff700] DEBUG - EventSource: Stopping.
Mar 12, 2021 07:50:04.780 [0x7fe60f0ed700] ERROR - Error issuing curl_easy_perform(handle): 6
Mar 12, 2021 07:50:04.780 [0x7fe60f0ed700] WARN - HTTP error requesting GET https://plex.tv/services/pubsub/servers (6, Couldn't resolve host name) (Could not resolve host: plex.tv)
Mar 12, 2021 07:50:07.381 [0x7fe60edff700] DEBUG - Completed: [192.168.1.161:51241] 200 GET /player/proxy/poll?deviceClass=pc&protocolVersion=3&protocolCapabilities=timeline%2Cplayback%2Cnavigation%2Cmirror%2Cplayqueues&timeout=1 (3 live) GZIP 20000ms 5 bytes (pipelined: 12)
Mar 12, 2021 07:50:07.385 [0x7fe60edff700] DEBUG - Auth: authenticated user 1 as anunez86
Mar 12, 2021 07:50:07.385 [0x7fe5d5cd7700] DEBUG - Request: [192.168.1.161:51241 (Subnet)] GET /player/proxy/poll?deviceClass=pc&protocolVersion=3&protocolCapabilities=timeline%2Cplayback%2Cnavigation%2Cmirror%2Cplayqueues&timeout=1 (3 live) GZIP Signed-in Token (anunez86)
Mar 12, 2021 07:50:07.385 [0x7fe5d5cd7700] DEBUG - Content-Length is -1 (of total: -1).