Took Synology update to DSM 7.2.2-72806, now Plex no longer working

[ChuckPa]

Did you change the permissions for the media shared folders?

Synology FAQ - Questions, Answers, and How-To's

FAQ 29 - DSM 7 - Give PlexMediaServer access to your media When you migrate to DSM 7, are installing a server for the first time, or just adding a new shared folder / sub-folder for media , folks forget to read the popup at the end of every installation which tells them about how to set permissions. This FAQ shows in detail how to do what those instructions state. When might you need to perform these steps? When upgrading, changing permissions from Plex to PlexMediaServer is overlook…

Going to need your server DEBUG logs ZIP file.
There is too much going on to guess.