Plex remote access issues - cannot connect securely

I have reset the certs of all affected users in this thread so far.
Please stop and restart your servers.

Please refer to your original post above for a moderator edit. If you are not affected by this particular issue, I have added a note in there.
Maybe take a look at Important note about Chrome and Firefox Local Network Access
and do also compare the hosted web app with the local web app.
Ensure that you are not on an old server version between 1.41.7.x to 1.42.0.x

If there are still issues, please open your own forum thread.